Alternative Names:

Anterior gradient protein 2 homolog; AG-2; hAG-2; HPC8; Secreted cement gland protein XAG-2 homolog; AGR2; AG2; GOB4; XAG2;

Application:

WB IHC ICC/IF IP FC

Reactivity:

Human

Dilution:

WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:20 FC 1:20

Western blot analysis of AGR2 expression in MCF-7 cell lysate.

Immunohistochemical analysis of paraffin-embedded human uterus, using AGR2 Antibody.

Purification:

Affinity-chromatography

Specificity:

AGR2 Antibody detects endogenous levels of AGR2

Immunogen:

A synthesized peptide derived from human AGR2

Description:

AGR2 is a member of the protein disulfide isomerase (PDI) family of proteins and a homolog of the Xenopus laevis cement gland protein. Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.