Alternative Names:
FAK; FADK; FAK1; FRNK; pp125FAK; PTK2;
Application:
WB IHC ICC/IF IP FC
Reactivity:
Human Mouse Rat
Dilution:
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:30 FC 1:50
 Western blot analysis of FAK expression in HeLa cell lysate. |
 Immunohistochemical analysis of paraffin-embedded mouse spleen, using FAK Antibody. |
 Immunofluorescent analysis of Hela cells, using FAK Antibody. |
Purification:
Affinity-chromatography
Specificity:
FAK Antibody detects endogenous levels of total FAK
Immunogen:
A synthesized peptide derived from human FAK
Description:
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix.
Storage Condition and Buffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
