Alternative Names:
Apopain precursor; CASP-3; CPP-32; CPP32; Caspase-3; Cysteine protease CPP32; ICE3; SCA-1; SREBP cleavage activity 1;
Application:
WB IHC IP
Reactivity:
Human Mouse Rat
Dilution:
WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50
Western blot analysis of Calreticulin expression in (1) Jurkat cell lysate; (2) COLO cells lysate. |
Immunohistochemical analysis of paraffin-embedded human stomach, using active + pro Caspase 3 Antibody . |
Purification:
Affinity-chromatography
Specificity:
active + pro Caspase 3 Antibody detects endogenous levels of total active + pro Caspase 3
Immunogen:
A synthesized peptide derived from human active + pro Caspase 3
Description:
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme.
Storage Condition and Buffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.