Alternative Names:
Medium-chain specific acyl-CoA dehydrogenase;MCAD; ACAD1; MCADH;ACADM
Application:
WB IHC ICC/IF IP
Reactivity:
Human Mouse Rat
Dilution:
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
Western blot analysis of ACADM expression in (1) HeLa cell lysate; (2) K562 cell lysate. |
Purification:
Affinity-chromatography
Specificity:
ACADM Antibody detects endogenous levels of total ACADM
Immunogen:
A synthesized peptide derived from human ACADM
Description:
This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Storage Condition and Buffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
