Alternative Names:
TNF receptor-associated factor 6; E3 ubiquitin-protein ligase TRAF6; Interleukin-1 signal transducer; RING finger protein 85; TRAF6; RNF85; TRAF 6; TRAF-6;
Application:
WB IHC ICC/IF
Reactivity:
Human Mouse Rat
Dilution:
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
Western blot analysis of TRAF6 expression in Jurkat cell lysate. |
Immunohistochemical analysis of paraffin-embedded human lung carcinoma, using TRAF6 Antibody. |
Purification:
Affinity-chromatography
Specificity:
TRAF6 Antibody detects endogenous levels of total TRAF6
Immunogen:
A synthesized peptide derived from human TRAF6
Description:
TRAFs (TNF receptor-associated factors) are a family of multifunctional adaptor proteins that bind to surface receptors and recruit additional proteins to form multiprotein signaling complexes capable of promoting cellular responses. Members of the TRAF family share a common carboxy-terminal TRAF domain which mediates interactions with associated proteins; many also contain amino-terminal Zinc/RING finger motifs.
Storage Condition and Buffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
