Alternative Names:
APRF, Acute-phase response factor, Signal transducer and activator of transcription 3
Application:
WB IHC ICC/IF FC
Reactivity:
Human Mouse Rat
Dilution:
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:100~1:500 FC 1:200~1:500
Western blot analysis of STAT3 expression in (1) A431 cell lysate; (2) Raji cell lysate. |
Immunohistochemical analysis of paraffin-embedded human thyroid carcinoma, using STAT3 Antibody. |
Immunofluorescent analysis of HeLa cells, using STAT3 Antibody. |
Purification:
Affinity-chromatography
Specificity:
STAT3 Antibody detects endogenous levels of total STAT3
Immunogen:
A synthesized peptide derived from human STAT3
Description:
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2.
Storage Condition and Buffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
