Alternative Names:
YY1, Delta transcription factor, INO80 complex subunit S, NF-E1, Yin and yang 1, YY-1
Application:
WB IHC ICC/IF IP
Reactivity:
Human Mouse Rat
Dilution:
WB 1:500~1:3000 IHC 1:50~1:200 ICC/IF 1:100~1:500 IP 1:50~1:100
Western blot analysis of YY1 expression in (1) HeLa cell lysate; (2) Daudi cell lysate. |
Immunohistochemical analysis of paraffin-embedded human bladder using YY1 Antibody. |
Immunofluorescent analysis of Hela cells, using YY1 Antibody. |
Purification:
Affinity-chromatography
Specificity:
YY1 Antibody detects endogenous levels of total YY1
Immunogen:
A synthesized peptide derived from human YY1
Description:
Its activity is regulated by transcription factors and cytoplasmic proteins that have been shown to abrogate or completely inhibit YY1-mediated activation or repression. For example, it acts as a repressor in absence of adenovirus E1A protein but as an activator in its presence. Acts synergistically with the SMAD1 and SMAD4 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
Storage Condition and Buffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
