Alternative Names:
TREB5; XBP1; XBP2;
Application:
WB IHC ICC/IF FC
Reactivity:
Human
Dilution:
WB 1:500~1:2000 IHC 1:100~1:500 ICC/IF 1:50~1:200 FC 1:50
Western blot analysis of XBP1 expression in Jurkat cell lysate. |
Purification:
Affinity-chromatography
Specificity:
XBP1 Antibody detects endogenous levels of total XBP1
Immunogen:
A synthesized peptide derived from human XBP1
Description:
Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I.
Storage Condition and Buffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
